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Carolina Panthers (2-6) at Cincinnati Bengals (4-4), 1 p.m., Fox

Line: Bengals -8 | Total: 43

The Bengals played one of their worst games of the season on Monday night against the Browns, and they were completely dismantled in a 32-13 loss on the road. The top receiver Ja’Marr Chase, is out indefinitely with a torn labrum and a fractured hip, and cornerback Chidobe Awuzie is out for the season with a torn anterior cruciate ligament. The Panthers are playing teams closely and 8 points might be one too many, even with the Bengals at home. Pick: Panthers +8

Green Bay Packers (3-5) at Detroit Lions (1-6), 1 p.m., Fox

Line: Lions +3.5 | Total: 50

The Packers got a sneaky half-point backdoor cover against the Bills last week thanks to a Jaire Alexander pick of Josh Allen in the fourth quarter. Green Bay will need to win outright as favorites on the road against Detroit, which has lost five games in a row.

The Lions looked great while building a 27-17 first-half lead against the Dolphins last week, but they didn’t score in the second half. This is a good spot for the Packers to try to snap their four-game losing streak, but the Lions won’t just roll over for them at home. They’ll look to fix their second-half woes. Pick: Lions +3.5

Indianapolis Colts (3-4-1) at New England Patriots (4-4), 1 p.m., Fox

Line: Patriots -5.5 | Total: 39.5

The Colts are tied for the most turnovers in the league with seven fumbles and nine interceptions. In his debut as the starter last week against Washington, a 17-16 loss, Sam Ehlinger lost only one fumble and didn’t throw any interceptions. He also didn’t throw any touchdowns. That’s an improvement, but it won’t cut it against a New England team that just goaded the Jets’ Zach Wilson into three picks last week. Pick: Patriots -5.5

Las Vegas Raiders (2-5) at Jacksonville Jaguars (2-6), 1 p.m., CBS

Line: Jaguars +1.5 | Total: 47.5

The Raiders haven’t won on the road this season and they didn’t come close last week, getting shut out by New Orleans as road favorites. Davante Adams, who was rumored to be sick, caught just one pass for 37 yards and Las Vegas didn’t cross midfield on a drive until the game’s final minutes.

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